MicroRNA-139 inhibits hepatocellular carcinoma cell growth through down-regulating karyopherin alpha 2

Abstract Background MicroRNA-139-5p (miR-139) has been shown to play important roles in hepatocellular carcinoma (HCC) development. However, the exact mechanism of miR-139 in HCC remains largely unknown. Methods We investigated the function in human cell lines and patient tissue samples by experimen...

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Bibliographic Details
Main Authors: Ying Zan, Baofeng Wang, Liang Liang, Yujiao Deng, Tian Tian, Zhijun Dai, Lei Dong
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-019-1175-2