LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2

LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2

Abstract Background Mounting evidence has suggested the essential role of long non-coding RNAs (lncRNAs) in a plethora of malignant tumors, including hepatocellular carcinoma. However, the underlyling mechanisms of lncRNAs remain unidentified in HCC. The present work was aimed to explore the regulat...

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Bibliographic Details
Main Authors: Guizhi Jia, Yan Wang, Chengjie Lin, Shihui Lai, Hongliang Dai, Zhiqian Wang, Luo Dai, Huizhao Su, Yanjie Song, Naiwen Zhang, Yukuan Feng, Bo Tang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
LINC01468
Hepatocellular carcinoma
Chemosensitivity
Aerobic glycolysis
miR-145-5p
Online Access:https://doi.org/10.1186/s13046-021-02090-7

Internet

https://doi.org/10.1186/s13046-021-02090-7

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