Regularized estimation of large-scale gene association networks using graphical Gaussian models

<p>Abstract</p> <p>Background</p> <p>Graphical Gaussian models are popular tools for the estimation of (undirected) gene association networks from microarray data. A key issue when the number of variables greatly exceeds the number of samples is the estimation of the ma...

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Bibliographic Details
Main Authors: Schäfer Juliane, Krämer Nicole, Boulesteix Anne-Laure
Format: Article
Language:English
Published: BMC 2009-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/10/384