Stimulation Modeling on Three-Dimensional Anisotropic Diffusion of MRI Tracer in the Brain Interstitial Space

Purpose: To build a mathematical model based magnetic resonance (MR) method to simulate drug anisotropic distribution in vivo in the interstitial space (ISS) of the brain.Materials and Methods: An injection of signal intensity-related gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA), which is...

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Bibliographic Details
Main Authors: Wei Wang, Qingyuan He, Jin Hou, Dehua Chui, Mingyong Gao, Aibo Wang, Hongbin Han, Huipo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroinformatics
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Online Access:https://www.frontiersin.org/article/10.3389/fninf.2019.00006/full