DEAD-box helicase proteins disrupt RNA tertiary structure through helix capture.

DEAD-box helicase proteins accelerate folding and rearrangements of highly structured RNAs and RNA-protein complexes (RNPs) in many essential cellular processes. Although DEAD-box proteins have been shown to use ATP to unwind short RNA helices, it is not known how they disrupt RNA tertiary structure...

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Bibliographic Details
Main Authors: Cynthia Pan, Jeffrey P Potratz, Brian Cannon, Zachary B Simpson, Jessica L Ziehr, Pilar Tijerina, Rick Russell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4211656?pdf=render