Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling
Defined signals that dictate the architecture of cellular boundaries in confluent cultures are poorly characterized. Here, we report dramatic remodeling, invoked by long-term epidermal growth factor (EGF) withdrawal from mammary-derived MCF10A cells. Such intervention generates an interdigitated, de...
Main Authors: | Wai Ying Yvonne Tang, Alison J. Beckett, Ian A. Prior, Judy M. Coulson, Sylvie Urbé, Michael J. Clague |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714007025 |
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