Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling

Defined signals that dictate the architecture of cellular boundaries in confluent cultures are poorly characterized. Here, we report dramatic remodeling, invoked by long-term epidermal growth factor (EGF) withdrawal from mammary-derived MCF10A cells. Such intervention generates an interdigitated, de...

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Bibliographic Details
Main Authors: Wai Ying Yvonne Tang, Alison J. Beckett, Ian A. Prior, Judy M. Coulson, Sylvie Urbé, Michael J. Clague
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714007025