A general approach to risk modeling using partial surrogate markers with application to perioperative acute kidney injury
Abstract Background Surrogate outcomes are often utilized when disease outcomes are difficult to directly measure. When a biological threshold effect exists, surrogate outcomes may only represent disease in specific subpopulations. We refer to these outcomes as “partial surrogate outcomes.” We hypot...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-12-01
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| Series: | Diagnostic and Prognostic Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41512-017-0022-1 |