Positive feedback cycle of TNFα promotes staphylococcal enterotoxin B-induced THP-1 cell apoptosis

Staphylococcal enterotoxin B (SEB) has been demonstrated to be of importance in Staphylococcus aureus related diseases, such as atopic dermatitis (AD). Dysregulated apoptosis in AD is remarkable, and SEB can induce apoptosis of various cell types. However, the mechanisms by which SEB induces apoptos...

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Main Authors: Xiaopeng Zhang, Weilong Shang, Jizhen Yuan, Zhen Hu, Huagang Peng, Junmin Zhu, Qiwen Hu, Yi Yang, Hui Liu, Bei Jiang, Yinan Wang, Shu Li, Xiaomei Hu, Xiancai Rao
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00109/full