Effect of cross-linked biodegradable polymers on sustained release of sodium diclofenac-loaded microspheres
The objective of this study was to formulate an oral sustained release delivery system of sodium diclofenac(DS) based on sodium alginate (SA) as a hydrophilic carrier in combination with chitosan (CH) and sodium carboxymethyl cellulose (SCMC) as drug release modifiers to overcome the drug-related ad...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2013-12-01
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Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400028&lng=en&tlng=en |