A Comparative Evaluation of a Novel Vaccine in APP/PS1 Mouse Models of Alzheimer’s Disease

Immunization against amyloid-beta-peptide (Aβ) has been widely investigated as a potential immunotherapeutic approach for Alzheimer’s disease (AD). With the aim of developing an active immunogenic vaccine without need of coadjuvant modification for human trials and therefore avoiding such side effec...

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Bibliographic Details
Main Authors: Iván Carrera, Ignacio Etcheverría, Lucía Fernández-Novoa, Valter Ruggero Maria Lombardi, Madepalli Krishnappa Lakshmana, Ramón Cacabelos, Carmen Vigo
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/807146