Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents

Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents

Gisele Zapata-Sudo,1,2 Isabelle Karine da Costa Nunes,2 Josenildo Segundo Chaves Araujo,1,2 Jaqueline Soares da Silva,2 Margarete Manhães Trachez,2,3 Tiago Fernandes da Silva,1 Filipe P da Costa,2 Roberto Takashi Sudo,1,2 Eliezer J Barreiro,1,2 Lídia Moreira Lima1,2 1National...

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Bibliographic Details
Main Authors: Zapata-Sudo G, da Costa Nunes IK, Araujo JSC, da Silva JS, Trachez MM, da Silva TF, da Costa FP, Sudo RT, Barreiro EJ, Lima LM
Format: Article
Language:English
Published: Dove Medical Press 2016-09-01
Series:Drug Design, Development and Therapy
Subjects:
diabetes
sulfonylhydrazone
hypoglycemic activity
druglikeness
plasma stability
metabolite.
Online Access:https://www.dovepress.com/synthesis-solubility-plasma-stability-and-pharmacological-evaluation-o-peer-reviewed-article-DDDT

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https://www.dovepress.com/synthesis-solubility-plasma-stability-and-pharmacological-evaluation-o-peer-reviewed-article-DDDT

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