Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity
The axon initial segment (AIS) is a specialized structure in neurons that resides in between axonal and somatodendritic domains. The localization of the AIS in neurons is ideal for its two major functions: it serves as the site of action potential firing and helps to maintain neuron polarity. It has...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
|
Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2016/6808293 |