Dissociation of natriuresis and diuresis by oxytocin molecular forms in rats.

In the rat, oxytocin (OT) produces dose-dependent diuretic and natriuretic responses. Post-translational enzymatic conversion of the OT biosynthetic precursor forms both mature and C-terminally extended peptides. The plasma concentrations of these C-terminally extended peptides (OT-G; OT-GK and OT-G...

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Bibliographic Details
Main Authors: Marek Jankowski, Bogdan A Danalache, Eric Plante, Ahmed Menaouar, Maria Florian, Ju Jing Tan, Ryszard Grygorczyk, Tom L Broderick, Jolanta Gutkowska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219205