A game of substrates: replication fork remodeling and its roles in genome stability and chemo-resistance

A game of substrates: replication fork remodeling and its roles in genome stability and chemo-resistance

During the hours that human cells spend in the DNA synthesis (S) phase of the cell cycle, they may encounter adversities such as DNA damage or shortage of nucleotides. Under these stresses, replication forks in DNA may experience slowing, stalling, and breakage. Fork remodeling mechanisms, which sta...

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Bibliographic Details
Main Author: Julia Sidorova
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-12-01
Series:Cell Stress
Subjects:
DNA
replication fork
S phase
end resection
human
vertebrate
chemotherapy
Online Access:http://www.cell-stress.com/researcharticles/a-game-of-substrates-replication-fork-remodeling-and-its-roles-in-genome-stability-and-chemo-resistance/

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http://www.cell-stress.com/researcharticles/a-game-of-substrates-replication-fork-remodeling-and-its-roles-in-genome-stability-and-chemo-resistance/

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