iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cre-dependent reporter and gene function analysis.
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-05-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10239-4 |