The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra.

The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra.

Presynaptic cannabinoid-1 receptors (CB1-R) bind endogenous and exogenous cannabinoids to modulate neurotransmitter release. CB1-Rs are expressed throughout the basal ganglia, including striatum and substantia nigra, where they play a role in learning and control of motivated actions. However, the p...

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Bibliographic Details
Main Authors: Margaret I Davis, Jill R Crittenden, Austin Y Feng, David A Kupferschmidt, Alipi Naydenov, Nephi Stella, Ann M Graybiel, David M Lovinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5821318?pdf=render

Internet

http://europepmc.org/articles/PMC5821318?pdf=render

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