Sequence analysis and molecular characterization of Clonorchis sinensis hexokinase, an unusual trimeric 50-kDa glucose-6-phosphate-sensitive allosteric enzyme.

Clonorchiasis, which is induced by the infection of Clonorchis sinensis (C. sinensis), is highly associated with cholangiocarcinoma. Because the available examination, treatment and interrupting transmission provide limited opportunities to prevent infection, it is urgent to develop integrated strat...

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Bibliographic Details
Main Authors: Tingjin Chen, Dan Ning, Hengchang Sun, Ran Li, Mei Shang, Xuerong Li, Xiaoyun Wang, Wenjun Chen, Chi Liang, Wenfang Li, Qiang Mao, Ye Li, Chuanhuan Deng, Lexun Wang, Zhongdao Wu, Yan Huang, Jin Xu, Xinbing Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169440?pdf=render