Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway

Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway

Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer. This article focuses on the cytotoxic activity of Euphorbia factor L2 against lung carcinoma A549 cells and the mechanism by which apo...

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Bibliographic Details
Main Authors: Minting Lin, Sili Tang, Chao Zhang, Hubiao Chen, Wenjing Huang, Yun Liu, Jianye Zhang
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Euphorbia Factor L2
Caper euphorbia seed
Euphorbia lathyris L.
Anticancer agent
Apoptosis
Mitochondrial pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383516300788

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http://www.sciencedirect.com/science/article/pii/S2211383516300788

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