Deacetylase activity-independent transcriptional activation by HDAC2 during TPA-induced HL-60 cell differentiation.

The human myeloid leukemia cell line HL-60 differentiate into monocytes following treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA). However, the mechanism underlying the differentiation of these cells in response to TPA has not been fully elucidated. In this study, we performed ChIP-seq pro...

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Bibliographic Details
Main Authors: Hyeonsoo Jung, Ji-Young Kim, Kee-Beom Kim, Yun-Cheol Chae, Yoonsoo Hahn, Jung-Woong Kim, Sang-Beom Seo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6108480?pdf=render