ABCA7 Risk Genotype Diminishes the Neuroprotective Value of Aerobic Fitness in Healthy Older African Americans

Although the association of ABCA7 risk variants with Alzheimer’s disease (AD) has been established worldwide, its effect size on the relative odds of being diagnosed with AD is significantly higher in African Americans. Across ethnicities, two common ABCA7 loci (rs115550680 and rs3764650) have been...

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Bibliographic Details
Main Authors: Chelsie N. Berg, Neha Sinha, Mark A. Gluck
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00073/full