Importance of Core Genome Functions for an Extreme Antibiotic Resistance Trait

Extreme antibiotic resistance in bacteria is associated with the expression of powerful inactivating enzymes and other functions encoded in accessory genomic elements. The contribution of core genome processes to high-level resistance in such bacteria has been unclear. In the work reported here, we...

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Bibliographic Details
Main Authors: Larry A. Gallagher, Samuel A. Lee, Colin Manoil, Howard A. Shuman
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e01655-17