A comprehensive assessment of multi-system responses to a renal inoculation of uropathogenic E. coli in swine.

<h4>Background</h4>The systemic responses to infection and its progression to sepsis remains poorly understood. Progress in the field has been stifled by the shortcomings of experimental models which include poor replication of the human condition. To address these challenges, we develop...

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Main Authors: Mohamad Hakam Tiba, Brendan M McCracken, Robert P Dickson, Jean A Nemzek, Carmen I Colmenero, Danielle C Leander, Thomas L Flott, Rodney C Daniels, Kristine E Konopka, J Scott VanEpps, Kathleen A Stringer, Kevin R Ward
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243577