Transplanted human fecal microbiota enhanced Guillain Barré syndrome autoantibody responses after Campylobacter jejuni infection in C57BL/6 mice

Transplanted human fecal microbiota enhanced Guillain Barré syndrome autoantibody responses after Campylobacter jejuni infection in C57BL/6 mice

Abstract Background Campylobacter jejuni is the leading antecedent infection to the autoimmune neuropathy Guillain-Barré syndrome (GBS), which is accompanied by an autoimmune anti-ganglioside antibody attack on peripheral nerves. Previously, we showed that contrasting immune responses mediate C. jej...

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Bibliographic Details
Main Authors: Phillip T. Brooks, Kelsey A. Brakel, Julia A. Bell, Christopher E. Bejcek, Trey Gilpin, Jean M. Brudvig, Linda S. Mansfield
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Microbiome
Subjects:
Campylobacter jejuni
Guillain-Barré syndrome
Commensal microbiota
Mouse models
Autoimmunity
Gastrointestinal inflammation
Online Access:http://link.springer.com/article/10.1186/s40168-017-0284-4

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http://link.springer.com/article/10.1186/s40168-017-0284-4

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