Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1

Low molecular weight reactive chemicals causing skin and respiratory allergies are known to activate dendritic cells (DC), an event considered to be a key step in both pathologies. Although generation of reactive oxygen species (ROS) is considered a major danger signal responsible for DC maturation,...

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Bibliographic Details
Main Authors: Isabel Ferreira, Ana Silva, João Demétrio Martins, Bruno Miguel Neves, Maria Teresa Cruz
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717309187