Bioassay-Guided Evaluation of Antinociceptive Effect of N-Salicyloyltryptamine: A Behavioral and Electrophysiological Approach

Bioassay-Guided Evaluation of Antinociceptive Effect of N-Salicyloyltryptamine: A Behavioral and Electrophysiological Approach

We investigated the antinociceptive and nerve excitability effects of the N-salicyloyltryptamine (NST) NST-treated mice exhibited a significant decrease in the number of writhes when 100 and 200 mg/kg (i.p.) were administered (i.p.). This effect was not antagonized by naloxone (1.5 mg/kg, i.p.). NST...

Full description

Bibliographic Details
Main Authors: Lucindo J. Quintans-Júnior, Davi A. Silva, Jullyana S. Siqueira, Adriano A. S. Araújo, Rosana S. S. Barreto, Leonardo R. Bonjardim, Josimari M. DeSantana, Waldeci De Lucca Júnior, Maria F. V. Souza, Stanley J. C. Gutierrez, José Maria Barbosa-Filho, Valter J. Santana-Filho, Demétrius A. M. Araújo, Reinaldo N. Almeida
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/230745

Internet

http://dx.doi.org/10.1155/2010/230745

Similar Items