CYP2J2 and EETs Protect Against Lung Ischemia/Reperfusion Injury via Anti-Inflammatory Effects in Vivo and in Vitro

CYP2J2 and EETs Protect Against Lung Ischemia/Reperfusion Injury via Anti-Inflammatory Effects in Vivo and in Vitro

Background: Injurious inflammatory response is critical to the development of lung ischemia/reperfusion injury (LIRI). The cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acid to epoxyeicosatrienoic acids (EETs), which exert an anti-inflammatory effect on the cardiovascular system....

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Bibliographic Details
Main Authors: Wenshu Chen, Shijiang Yang, Wei Ping, Xiangning Fu, Qinzi Xu, Jianing Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Lung ischemia/reperfusion injury
Inflammation
Cytochrome P450 epoxygenase 2J2
Epoxyeicosatrienoic acid
Online Access:http://www.karger.com/Article/FullText/374011

Internet

http://www.karger.com/Article/FullText/374011

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