Necroptotic‐susceptible dendritic cells exhibit enhanced antitumor activities in mice

Abstract Introduction Priming of tumor‐specific T cells is a key to antitumor immune response and inflammation, in turn, is crucial for proper T‐cell activation. As antigen‐presenting cells can activate T cells, dendritic cells (DCs) loaded with tumor antigens have been used as immunotherapeutics ag...

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Bibliographic Details
Main Authors: Zhanran Zhao, Guangzhi Zhang, Yuefang Sun, Astar Winoto
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.330