Mammalian STE20-Like Kinase 2 Promotes Lipopolysaccharides-Mediated Cardiomyocyte Inflammation and Apoptosis by Enhancing Mitochondrial Fission

Mammalian STE20-Like Kinase 2 Promotes Lipopolysaccharides-Mediated Cardiomyocyte Inflammation and Apoptosis by Enhancing Mitochondrial Fission

In this study, we analyzed the role of mammalian STE20-like protein kinase 2 (Mst2), a serine-threonine protein kinase, in Lipopolysaccharides (LPS)-mediated inflammation and apoptosis in the H9C2 cardiomyocytes. Mst2 mRNA and protein levels were significantly upregulated in the LPS-treated H9C2 car...

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Bibliographic Details
Main Authors: Yanan Tian, Haijiu Song, Wei Qin, Zhenjiang Ding, Ying Zhang, Weichao Shan, Dapeng Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
Mst2
inflammation
mitochondrial fission
cardiomyocyte
FCCP
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00897/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00897/full

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