Response Surface Methodology for Optimization of Process Variables of Atorvastatin Suspension Preparation by Microprecipitation Method Using Desirability Function

Background: Atorvastatin (AT), as a synthetic lipid-lowering agent, is a highly crystalline substance having poor solubility and low bioavailability. The objective of the present research was to improve the microprecipitation method of AT suspension preparation. Methods: Microprecipitation parameter...

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Bibliographic Details
Main Authors: Maryam Maghsoodi, Seyed hassan Montazam, Hossein Rezvantalab, Mitra Jelvehgari
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-03-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:https://ps.tbzmed.ac.ir/PDF/Pharm-32837