Response Surface Methodology for Optimization of Process Variables of Atorvastatin Suspension Preparation by Microprecipitation Method Using Desirability Function
Background: Atorvastatin (AT), as a synthetic lipid-lowering agent, is a highly crystalline substance having poor solubility and low bioavailability. The objective of the present research was to improve the microprecipitation method of AT suspension preparation. Methods: Microprecipitation parameter...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2020-03-01
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Series: | Pharmaceutical Sciences |
Subjects: | |
Online Access: | https://ps.tbzmed.ac.ir/PDF/Pharm-32837 |