Progress in RNAi-mediated Molecular Therapy of Acute and Chronic Myeloid Leukemia

Progress in RNAi-mediated Molecular Therapy of Acute and Chronic Myeloid Leukemia

Leukemias arise from genetic alterations in normal hematopoietic stem or progenitor cells, leading to impaired regulation of proliferation, differentiation, apoptosis, and survival of the transformed cells. With the advent of RNA interference (RNAi) and the short interfering RNA (siRNA) as its pharm...

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Bibliographic Details
Main Authors: Breanne Landry, Juliana Valencia-Serna, Hilal Gul-Uludag, Xiaoyan Jiang, Anna Janowska-Wieczorek, Joseph Brandwein, Hasan Uludag
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
drug delivery
leukemia
molecular therapy
nonviral vectors
nanoparticles
RNAi
siRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116300257

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http://www.sciencedirect.com/science/article/pii/S2162253116300257

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