Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population

Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population

A recent paper reported that Aβ oligomer causes neuronal cell death through the phosphatidylinositol-3-OH kinase (PI3K)-Akt-mTOR signaling pathway. Intraneuronal Aβ, a main pathological finding of Alzheimer's disease (AD), is also known as inhibiting activation of Akt. This study aims to invest...

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Bibliographic Details
Main Authors:	Nobuto Shibata, Tohru Ohnuma, Bolati Kuerban, Miwa Komatsu, Hajime Baba, Heii Arai
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	International Journal of Alzheimer's Disease
Online Access:	http://dx.doi.org/10.4061/2011/762471

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