Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population
A recent paper reported that Aβ oligomer causes neuronal cell death through the phosphatidylinositol-3-OH kinase (PI3K)-Akt-mTOR signaling pathway. Intraneuronal Aβ, a main pathological finding of Alzheimer's disease (AD), is also known as inhibiting activation of Akt. This study aims to invest...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
|
Series: | International Journal of Alzheimer's Disease |
Online Access: | http://dx.doi.org/10.4061/2011/762471 |