The class I PI3K/Akt pathway is critical for cancer cell survival in dogs and offers an opportunity for therapeutic intervention

The class I PI3K/Akt pathway is critical for cancer cell survival in dogs and offers an opportunity for therapeutic intervention

<p>Abstract</p> <p>Background</p> <p>Using novel small-molecular inhibitors, we explored the feasibility of the class I PI3K/Akt/mTORC1 signaling pathway as a therapeutic target in canine oncology either by using pathway inhibitors alone, in combination or combined with...

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Bibliographic Details
Main Authors: Chen Yu-Ting, Tan Karen AL, Pang Lisa Y, Argyle David J
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Veterinary Research
Subjects:
Canine
Cancer
PI3
AKT
MTOR
Therapeutic
Target
Online Access:http://www.biomedcentral.com/1746-6148/8/73

Internet

http://www.biomedcentral.com/1746-6148/8/73

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