Characterization of genomic DNA of lactic acid bacteria for activation of plasmacytoid dendritic cells

Abstract Background Lactococcus lactis strain Plasma (LC-Plasma) possesses strong stimulatory activity for plasmacytoid dendritic cells (pDCs) via the TLR9-Myd88 pathway. To reveal the effective lactic acid bacteria (LAB) genome structure for pDCs stimulatory activity, we performed in vitro screenin...

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Bibliographic Details
Main Authors: Akira Horie, Yasuyuki Tomita, Konomi Ohshio, Daisuke Fujiwara, Toshio Fujii
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Microbiology
Subjects:
CpG
Online Access:http://link.springer.com/article/10.1186/s12866-019-1458-y