The Cardioprotective Effect of Hypertonic Saline Is Associated with Inhibitory Effect on Macrophage Migration Inhibitory Factor in Sepsis

Sepsis can cause myocardial dysfunction, which contributes to the high mortality of sepsis. Hypertonic saline (HS) has been reported to increase myocardial contractility in sepsis. In the present study, mechanisms of action of HS resuscitation (4 mL of 7.5% NaCl per kilogram) on cardiac function hav...

Full description

Bibliographic Details
Main Authors: Yi-Li Wang, Kwok-Keung Lam, Pao-Yun Cheng, Ching-Wen Kung, Shu-Ying Chen, Chun-Chih Chao, Hwong-Ru Hwang, Ming-Ting Chung, Yen-Mei Lee
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/201614