Direct and Propagated Effects of Small Molecules on Protein-Protein Interaction Networks
Networks of protein-protein interactions (PPIs) link all aspects of cellular biology. Dysfunction in the assembly or dynamics of PPI networks is a hallmark of human disease, and as such, there is growing interest in the discovery of small molecules that either promote or inhibit PPIs. Protein-protei...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-08-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00119/full |