Dealing with Misfolded Proteins: Examining the Neuroprotective Role of Molecular Chaperones in Neurodegeneration

Human neurodegenerative diseases arise from a wide array of genetic and environmental factors. Despite the diversity in etiology, many of these diseases are considered "conformational" in nature, characterized by the accumulation of pathological, misfolded proteins. These misfolded protein...

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Bibliographic Details
Main Authors: R. Grace Zhai, Yousuf O. Ali, Brandon M. Kitay
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/10/6859/