Dietary Glycotoxins Impair Hepatic Lipidemic Profile in Diet-Induced Obese Rats Causing Hepatic Oxidative Stress and Insulin Resistance

Nonalcoholic fatty liver disease (NAFLD) is caused by excessive liver lipid accumulation, but insulin resistance is specifically associated with impaired lipid saturation, oxidation, and storage (esterification), besides increased de novo lipogenesis. We hypothesized that dietary glycotoxins could i...

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Bibliographic Details
Main Authors: C. Neves, T. Rodrigues, J. Sereno, C. Simões, J. Castelhano, J. Gonçalves, G. Bento, S. Gonçalves, R. Seiça, M. R. Domingues, M. Castelo-Branco, P. Matafome
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/6362910