A Delicate Balance: Role of MMP-9 in Brain Development and Pathophysiology of Neurodevelopmental Disorders

A Delicate Balance: Role of MMP-9 in Brain Development and Pathophysiology of Neurodevelopmental Disorders

The extracellular matrix (ECM) is a critical regulator of neural network development and plasticity. As neuronal circuits develop, the extracellular matrix stabilizes synaptic contacts, while its cleavage has both permissive and active roles in the regulation of plasticity. Matrix Metalloproteinas...

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Bibliographic Details
Main Authors: Sarah Marie Reinhard, Khaleel eRazak, Iryna eEthell
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Cerebellum
Epilepsy
Extracellular Matrix
Fragile X Syndrome
Hippocampus
critical period
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00280/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00280/full

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