Sequential MCR via Staudinger/Aza-Wittig versus Cycloaddition Reaction to Access Diversely Functionalized 1-Amino-1<i>H</i>-Imidazole-2(3<i>H</i>)-Thiones

Sequential MCR via Staudinger/Aza-Wittig versus Cycloaddition Reaction to Access Diversely Functionalized 1-Amino-1<i>H</i>-Imidazole-2(3<i>H</i>)-Thiones

A multicomponent reaction (MCR) strategy, alternative to the known cycloaddition reaction, towards variously substituted 1-amino-1<i>H</i>-imidazole-2(3<i>H</i>)-thione derivatives has been successfully developed. The novel approach involves &#945;-halohydrazones whose az...

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Bibliographic Details
Main Authors: Cecilia Ciccolini, Giacomo Mari, Gianfranco Favi, Fabio Mantellini, Lucia De Crescentini, Stefania Santeusanio
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
multicomponent reaction
α-halohydrazones
staudinger reaction
aza-wittig
1<i>h</i>-imidazole-2(3<i>h</i>)-thione
2<i>h</i>-imidazo[2,1-<i>b</i>][1,3,4]thiadiazine
Online Access:https://www.mdpi.com/1420-3049/24/20/3785

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https://www.mdpi.com/1420-3049/24/20/3785

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