Adiposity significantly modifies genetic risk for dyslipidemia[S]

Recent genome-wide association studies have identified multiple loci robustly associated with plasma lipids, which also contribute to extreme lipid phenotypes. However, these common genetic variants explain <12% of variation in lipid traits. Adiposity is also an important determinant of plasma li...

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Bibliographic Details
Main Authors: Christopher B. Cole, Majid Nikpay, Paulina Lau, Alexandre F.R. Stewart, Robert W. Davies, George A. Wells, Robert Dent, Ruth McPherson
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349932