Role of O6-methylguanine-DNA methyltransferase and p53 in response of neuroblastoma cells to an alkylating agent temozolomide

Aim. To study the role of p53 and O6-methylguanine-DNA methyltransferase in sensitivity of neuroblastoma cells to temozolomide. Methods. The study was performed on SK.N.SH neuroblastoma cell line cultured in DMEM medium supplemented with fetal bovine serum and antibiotics penicillin-streptomycin...

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Bibliographic Details
Main Authors: R R Khusnutdinov, S V Boychuk
Format: Article
Language:Russian
Published: ECO-vector 2018-02-01
Series:Kazanskij Medicinskij Žurnal
Subjects:
Online Access:https://journals.eco-vector.com/kazanmedj/article/view/7808