Biochemical properties, tissue expression, and gene structure of a short chain dehydrogenase/reductase able to catalyze cis-retinol oxidation

We have identified a retinol dehydrogenase (cRDH) that catalyzes the oxidation of 9-cis- but not all-trans-retinol and proposed that this enzyme plays an important role in synthesis of the transcriptionally active retinoid, 9-cis-retinoic acid. There is little information regarding either the bioche...

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Bibliographic Details
Main Authors: Mary V. Gamble, Enyuan Shang, Roseann Piantedosi Zott, James R. Mertz, Debra J. Wolgemuth, William S. Blaner
Format: Article
Language:English
Published: Elsevier 1999-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520321039