Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression

<p>Abstract</p> <p>Background</p> <p>In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a complex network that regulate the state of chromatin and processes that...

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Bibliographic Details
Main Authors: Xu Xiaojiang, Hoang Stephen, Mayo Marty W, Bekiranov Stefan
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/396