Effects of BRCA1 Transgene Expression on Murine Mammary Gland Development and Mutagen-Induced Mammary Neoplasia

Effects of BRCA1 Transgene Expression on Murine Mammary Gland Development and Mutagen-Induced Mammary Neoplasia

<p>To characterize the role of <i>BRCA1</i> in mammary gland development and tumor suppression, a transgenic mouse model of <i>BRCA1</i> overexpression was developed. Using the mouse mammary tumor virus (MMTV) promoter/enhancer, transgenic mice expressing human BRCA1 or...

Full description

Bibliographic Details
Main Author: Arichika Hoshino, Cindy J. Yee, Mel Campbell, Randall L. Woltjer, Rebecca L. Townsend, Riet van der Meer, Yu Shyr, Jeffrey T. Holt, Harold L. Moses, Roy A. Jensen
Format: Article
Language:English
Published: Ivyspring International Publisher 2007-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v03p0281.htm

Internet

http://www.biolsci.org/v03p0281.htm

Similar Items