Global Analysis of Enhancer Targets Reveals Convergent Enhancer-Driven Regulatory Modules

Summary: Single-cell screens enable high-throughput functional assessment of enhancers in their endogenous genomic context. However, the design of current studies limits their application to identifying the primary gene targets of enhancers. Here, we improve the experimental and computational parame...

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Bibliographic Details
Main Authors: Shiqi Xie, Daniel Armendariz, Pei Zhou, Jialei Duan, Gary C. Hon
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719313956