Development of a bioanalytical method for circulating human T cells in animals using Arthrobacter luteus-based quantitative polymerase chain reaction and its application in preclinical biodistribution studies

Introduction: In the development of cell therapy products for human use, studies on the biodistribution of transplanted cells in animals are important for assessing the safety and efficacy of these products. Although a few reports have described the biodistribution of human cells in animals using Ar...

Full description

Bibliographic Details
Main Authors: Hisao Shimizu, Yoji Kuze, Tomoaki Higuchi, Shin-ichi Matsumoto, Syunsuke Yamamoto, Akihiko Goto, Yuu Moriya, Hideki Hirabayashi
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300791