A Systematic Review of the Efficacy of Preclinical Models of Lung Cancer Drugs

Background: Preclinical cell models are the mainstay in the early stages of drug development. We sought to explore the preclinical data that differentiated successful from failed therapeutic agents in lung cancer.Methods: One hundred thirty-four failed lung cancer drugs and twenty seven successful l...

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Bibliographic Details
Main Authors: Elizabeth Pan, David Bogumil, Victoria Cortessis, Sherrie Yu, Jorge Nieva
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00591/full