PD-1 of Sigmodon hispidus: Gene identification, characterization and preliminary evaluation of expression in inactivated RSV vaccine-induced enhanced respiratory disease

Abstract Sigmodon hispidus or cotton rat is an excellent animal model for studying human infections of respiratory viruses including respiratory syncytial virus (RSV), which is the leading cause of hospitalization in infants and causes high rates of infection in the elderly and immunocompromised pat...

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Bibliographic Details
Main Authors: Abenaya Muralidharan, Louise Larocque, Marsha Russell, Marybeth Creskey, Changgui Li, Wangxue Chen, Gary Van Domselaar, Jingxin Cao, Terry Cyr, Michael Rosu-Myles, Lisheng Wang, Xuguang Li
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48225-x